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Chrono™ Senso-DM

Human pluripotent stem cell differentiation medium for the rapid manufacture of nociceptors by end users.


Already in use for pain-drug discovery, Chrono™ Senso-DM has proven effective for pain modeling. With a reliable and reproducible source of nociceptors, drug discovery is no longer constrained by unacceptably long setup times common for other hiPSC-derived sensory neurons.

Anatomic's breakthrough in producing ectoderm from hiPSCs within 24 hours provides near-immediate access to engineering neuron diversity unique to the nervous system. Chrono™ Senso-DM builds upon these findings to produce a highly pure population of immature sensory neurons within only seven days.

Chrono™ Senso-DM is a human pluripotent stem cell differentiation (hiPSC) kit that allowing researchers to rapidly manufacture nociceptors at the scale needed for their laboratory. Suitable for pharmaceutical companies, academic research settings and other research facilities, this differentiation media removes the barriers to efficient assay development and compound screening.

Streamline Your Research

By allowing neuroscience researchers to manufacture sensory neurons, entire research teams can develop new workflows, streamline processes and focus on innovation and results.


Chrono™ Senso-DM produces differentiation of human pluripotent stem cells into dorsal root ganglia-like sensory neurons faster than ever, with a pure population of immature sensory neurons in seven days.


Manufactures up to 10 million sensory neurons with 90% purity for BRN3A, ISL1


Quality Controlled

To eliminate variability, Chrono™ Senso-DM uses serum-free, chemically defined media and has been validated for use downstream from multiple defined systems for the undifferentiated culture of hiPSCs.

Successful Production of hiPSC-Derived Sensory Neurons

Chrono™ Senso-DM requires only standard laboratory equipment and is designed for use by researchers of all skill levels. The easy-to-complete production of human pluripotent stem cell-derived sensory neurons is part of a complementary suite of sensory neuron products for a variety of research interests.

  • Chrono™ Senso-MM: for the rapid maturation of ion channels and electrophysical activity

  • RealDRG™: cryopreserved sensory neurons for off-the-shelf use

Anatomic's Chrono™ Senso-DM was developed to put the power of your research back into your own hands. User-friendly, high-quality and researcher-focused, our human pluripotent stem cell differentiation kit allows your lab to consistently innovate, experiment and discover new pain treatments faster and more reliably than ever before.

Contact us today for more information about Chrono™ Senso-DM hiPSC-derived sensory neuron differentiation medium.

Chrono™ Senso-DM Resources

Find product manuals and other useful documentation for this product.

Senso-DM Product Manual

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